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Eric V. Granowitz, MD

Medicine Department   Image  
Infectious Diseases Division
  • Associate Professor of Medicine, Tufts University School of Medicine
  • Adjunct Professor, University of Massachusets - Amherst
  • Adjunct Professor, Springfield College
Baystate Infectious Diseases
3300 Main Street, Suites 3C&D
Springfield, MA 01199
  • Fellowship, Division of Geographic Medicine and Infectious Diseases
    New England Medical Center/Tufts University School of Medicine
    Boston, MA
  • Medicine Residency, Barnes Hospital/Washington University School of Medicine
    St. Louis, MO
  • Columbia University College of Physicians and Surgeons
    New York, NY
Areas of Interest
  • Cytokines
  • Apoptosis
  • Medical Education


  • Furua EY, Paez A, Srinivasan A, Cooksey R, Augenbraun M, Baron M, Brudney K, Della-Latta P, Estivariz C, Fischer S, Flood M, Kellner P, Roman C, Yakrus M, Weiss D, Granowitz EV. Outbreak of Mycobacterium abscessus wound infections in US "lipotourists" who underwent abdominoplasty in the Dominican Republic, Clin Infect Dis 2008; 46:1181-1188.
  • Granowitz EV, Srinivasan A, Clynes ND.  Using the internet to identify infectious-disease outbreaks.  NEJM 2004; 351:2558-2589.
  • Granowitz EV, Longworth DL.  Risk stratification and bedside prognostication in infective endocarditis.  JAMA 2003;289:1991-1993.
  • Benson RM, Minter LM, Osborne BA, Granowitz EV.  Hyperbaric oxygen inhibits stimulus-induced pro-inflammatory cytokine synthesis by human blood-derived monocyte-macrophages.  Clin Exp Immunol 2003;134:57-62.
  • Ganguly BJ, Tonomura N, Benson RM, Osborne BA, Granowitz EV.  Hyperbaric oxygen enhances apoptosis in hematopoietic cells.  Apoptosis 2002;7:499-510.
  • Wolf LE, Gorbach SL, Granowitz EV.  Extraintestinal Clostridium difficile: 10 years’ experience at a tertiary-care hospital.  Mayo Clin Proc 1998;73:943-947.
  • Granowitz EV.  Transforming growth factor-b enhances and pro-inflammatory cytokines inhibit ob gene expression in 3T3-L1 adipocytes.  Biochem Biophys Res Comm 1997;240:382-385.
  • Granowitz EV, Saget BM, Wang MZ, Dinarello CA, Skolnik PR.  Interleukin-1 induces HIV-1 expression in chronically-infected U1 cells:  blockade by interleukin-1 receptor antagonist and tumor necrosis factor binding protein type I.  Molecular Medicine 1995;1:667-677.
  • Granowitz EV, Porat R, Mier JW, Orencole SF, Kaplanski G, Lynch EA, Ye K, Vannier E, Wolff SM, Dinarello CA.  Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans.  J Immunol 1993; 5:637-645.
  • Granowitz EV, Porat R, Mier JW, Pribble JP, Stiles DM, Bloedow DC, Catalano MA, Wolff SM, Dinarello CA.  Pharmacokinetics, safety, and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans.  Cytokine 1992;4:353-360.
  • Granowitz EV, Vannier E, Poutsiaka DD, Dinarello CA.  Effect of interleukin 1 blockade on cytokine syntheses.  II. Interleukin 1 receptor antagonist inhibits lipopolysaccharide induced cytokine synthesis by human monocytes.  Blood 1992;79:2365-2369.
  • Granowitz EV, Santos AA, Poutsiaka DD, Cannon JG, Wilmore DG, Wolff SM, Dinarello CA.  Interleukin-1 receptor antagonist production during experimental endotoxaemia. Lancet 1991; 338:1423-1424.
  • Granowitz EV, Clark BD, Mancilla J, Dinarello CA.  Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor. J Biol Chem 1991;266:14147-14150.