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NHLBI R21 Grant to Study PAP Use in Surgery Patients with Apnea Awarded to Dr. Peter Lindenauer

November 01, 2013

Dr. Peter LindenauerDr. Peter Lindenauer, Director of the Center for Quality of Care Research, has been awarded a R21 grant from NHLBI/NIH for a 2-year study, "Perioperative Use and Outcomes of Noninvasive Ventilation in Sleep Apnea". Also on the project are Mihaela Stefan MD and Penny Pekow PhD from Baystate, and Nicholas Hill MD from TUSM, an internationally recognized expert in use of PAP.

The intent of the study is to yield new knowledge about the adoption and effectiveness of noninvasive ventilation in patients with obstructive sleep apnea undergoing major non-cardiac surgery.

"Patients with obstructive sleep apnea who have surgery have a significantly increased risk of adverse outcomes. Now it's common to screen for apnea pre-op and put those patients on PAP devices. But there really isn’t data that shows they help post-op," states Dr. Lindenauer.

This project will look at patients with sleep apnea who undergo major surgery and get CPAP and biPAP to determine if they have a lower risk of complications in the first couple of days post-op. The researchers will also look at whether certain patients are more likely to get PAP, and whether the benefits of PAP therapy vary according to certain patient characteristics, such as age.